E-cigarettes reduce the potential damage to DNA significantly compared to traditional cigarettes

Although previous studies have pointed out that ingesting the e-liquid after atomization is not necessarily so healthy. However, a new study recently submitted to the journal Mutagenesis still points out that switching from traditional tobacco products to e-cigarettes may still help reduce potential damage to human DNA. It is reported that this study aims to evaluate the effects of tobacco smoke and atomized e-liquid on cells, such as the possibility of damage to proteins and DNA.

It is reported that the research involves six sets of reporter gene cell lines tested and analyzed by ToxTracker, and it is also the first time that a team has used this system to study e-liquid and aerosols.

In addition to cell protein and DNA damage, the research team also evaluated the oxidative stress of tobacco smoke and atomized e-liquid, as well as the activation of genes that inhibit tumors and regulate the cell cycle.

As a result, it was found that undiluted aerosolized e-liquid and aerosols can greatly reduce, or even show no signs of potential damage to DNA in cells.

Even if the concentration of nicotine is tens of thousands of times higher than that of traditional tobacco, it will only produce oxidative stress (especially a state where the body’s oxidation and antioxidant effects are out of balance).

In addition, the mist-like aerosols produced by heating the e-liquid did not trigger any detectable reactions in the six tested cell lines.

The first study, Lukasz Czekala, said: “In general, the new research data has increased the amount of scientific evidence for related theories. That is, compared with combustible cigarettes, e-cigarettes have the potential to significantly reduce harm.”

After successfully passing the peer review, this article is expected to be officially published in the new issue of Mutagenesis journal.

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