According to the latest paper published by CDC researchers, the content of NNAL, a metabolite of tobacco specific nitrosamines (TSNA), in the urine of e-cigarette users is very low, only 2.2% of that of cigarette users, and 0.6% of that of smokeless tobacco users (snuff, chewing tobacco, etc.).
The research results once again prove that the harm of e-cigarette is much lower than that of traditional tobacco, and there is no second-hand smoke problem of traditional tobacco.
Note: screenshots of the latest papers published by CDC researchers
More than 70 kinds of carcinogens have been identified in traditional tobacco and second-hand smoke. Among them, tobacco specific nitrosamine (TSNA) is the most important carcinogen in tobacco and its combustion smoke, which is very harmful to the health of smokers and second-hand smokers. TSNA includes NNK, NNN, nab, NAT, etc. The World Health Organization (who) has determined that NNK and NNN are the main factors causing the carcinogenicity of cigarette smoke.
The study lasted for seven years and began to collect epidemiological data on tobacco use behavior from 2013, including use patterns, attitudes, habits and health effects, and to assess the impact of relevant tobacco regulatory policies of the food and Drug Administration (FDA). This paper is the first phase of the study, mainly monitoring the urine NNAL concentration of the first wave (W1) of the path study conducted from September 12, 2013 to December 15, 2014.
NNAL is a metabolite produced by the treatment of nitrosamines (TSNAs) in human body, which is excreted through urine. People inhale nitrosamine (TSNA) by using tobacco products or secondhand smoke, and then excrete the metabolite NNAL in urine.
The results showed that the average concentration of NNAL in the urine of smokeless tobacco users was 993.3 ng / g creatinine, that of cigarette users was 285.4 ng / g creatinine, and that of electronic cigarette users was 6.3 ng / g creatinine. That is to say, the content of NNAL in the urine of e-cigarette users was only 2.2% of that of cigarette users, which was 0.6% of that of smokeless tobacco users.
This study is not the first time that CDC has published evidence that e-cigarettes do not have second-hand smoke problems of traditional tobacco. As early as 2014, CDC researchers published research papers on VOCs (volatile organic compounds) in the smoke of traditional tobacco and e-cigarette. The results showed that the content of VOCs metabolite VOCs in the urine of e-cigarette users was similar to that of non-smokers, while the concentration of VOCs in smokers was significantly higher than that of e-cigarette users, smokeless tobacco users and never smokers. Vocms are metabolites of VOCs produced by human body, which are excreted by urine.
Note: screenshots of papers published by CDC researchers in 2014
VOCs (volatile organic compounds) are the general term of volatile organic compounds under certain conditions. Benzene, toluene, formaldehyde and other harmful substances commonly known by people all belong to the category of VOCs.
TSNA (nitrosamines) and VOCs (volatile organic compounds) are the two most important carcinogenic harmful substances in traditional tobacco second-hand smoke. The above-mentioned research of CDC has proved that e-cigarette does not have the problem of second-hand smoke similar to traditional tobacco.
This also shows that it is lack of scientific basis and absurd to confuse e-cigarette with traditional tobacco, and even take the harm of second-hand smoke of traditional tobacco as evidence to classify e-cigarette into indoor tobacco control category.