The agency has operated without a permanent commissioner for more than a year. Acting Commissioner Janet Woodcock has filled the FDA leadership role since President Joe Biden’s inauguration last January, and Biden didn’t seek a candidate for the permanent position until nominating Califf in November.
Califf, who also served as FDA commissioner during President Obama’s final year in office, faced some Democratic opposition based on his handling of the opioid crisis and connections to the drug industry. More threatening to Califf’s confirmation was opposition from anti-abortion groups angry over the FDA’s loosening of abortion pill rules.
In January and February, the White House and special interest groups who support Califf engaged in a concentrated push to save the nomination, according to the Washington Post. The nominee himself made promises to several senators to secure their votes.
In the end, just four Democrats—Richard Blumenthal (CT), Maggie Hassan (NH), Joe Manchin (WV), and Edward Markey (MA)—joined Vermont independent Sen. Bernie Sanders (who caucuses with the Democrats) and most Republicans to vote against the former Duke cardiologist and researcher.
Six Republicans—Roy Blunt (MO), Richard Burr (NC), Susan Collins (ME), Lisa Murkowski (AK), Mitt Romney (UT), and Pat Toomey (PA)—crossed party lines to vote for President Biden’s nominee. Four senators didn’t cast a vote.
The final 50-46 vote came one day after a procedural vote indicated Califf was likely to receive Senate approval. In 2016, Califf was confirmed by an 89-4 margin, with three Democrats and just one Republican voting against the nominee.
Califf’s confirmation was strongly supported by most anti-vaping and tobacco control organizations, including the Campaign for Tobacco-Free Kids. They want the next FDA commissioner to ban flavored vaping products and menthol cigarettes, and issue a rule reducing nicotine in all cigarettes to non-addictive levels.