The study compared the effectiveness of nicotine e-cigs with licensed nicotine replacement therapies (NRTs) and nicotine-free based control conditions, for smoking cessation.
Titled, “A systematic review of randomized controlled trials and network meta-analysis of e-cigarettes for smoking cessation,” the study compared the effectiveness of nicotine e-cigarettes for smoking cessation with licensed nicotine replacement therapies (NRT) and nicotine-free based control conditions.
The researchers searched PubMed, Web of Science and PsycINFO for randomised controlled trials (RCTs) that allocated individuals to use nicotine e-cigarettes, compared to those that used licensed NRT (e.g., nicotine patches, nicotine gums, etc), or a placebo. The research team selected only studies which included smoking participants who were healthy.
Sifting through data from thousands of studies, the research team identified that smokers who turned to nicotine e-cigarettes were more likely to remain abstinent from smoking than those in the control condition. “Smokers assigned to use nicotine e-cigarettes were more likely to remain abstinent from smoking than those assigned to use licensed NRT, and both were more effective than usual care or placebo conditions. More high quality studies are required to ascertain the effect of e-cigarette on smoking cessation due to risk of bias in the included studies,” concluded the study.